Transfers Empty Capsules to Filling Machine

The CapsuJet C20 from Hanningfield is an engineered-to-order empty capsule transfer system designed for seamless integration into pharmaceutical and nutraceutical production lines. What sets the CapsuJet C20 apart is its use of a patented venturi system that gently conveys empty capsules at a high throughput of 300,000 capsules per hour. It is adept at handling all hard shell capsule sizes, including gelatin, HPMC, and vegetable capsules, ensuring minimal to zero capsule damage. The system is compatible with continuous, automated operations, operated via a fully adjustable optical sensor that optimizes the capsule flow by regulating the convey cycle. Its construction in 316L stainless steel for contact parts and 304 stainless steel for non-contact parts ensures durability and compliance with cleanroom standards. The mobile trolley design allows for flexible installation, while the adjustable dimensions allow for customization based on specific production needs. The CapsuJet C20 is best suited for applications in the pharmaceutical, food and beverage, chemical, cannabis, and nutraceutical industries, providing efficient solutions for pre-processing, processing, and packaging departments.

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Controls and Regulates Powder Flow

The Powder Flow Control System from Hanningfield is specifically designed to manage the precise flow and dosing of powders in industries ranging from pharmaceuticals to nutraceuticals and chemicals. It features a rotary valve system that facilitates continuous and automated operation, ensuring seamless powder transfers with minimal risk of spillage or overloading. Its ability to integrate with existing site machinery enhances control, as level sensors automate powder flow management, activating only when needed to prevent material excess.

Primarily used in applications involving tablets, vitamin supplements, APIs, and cannabis products, the system supports efficient processing by maintaining an optimal flow rate of powders, critical for processes like compression and encapsulation. Constructed with 316L stainless steel and FDA-compliant seals, it meets strict industry standards for hygiene and safety, making it suitable for sectors demanding high compliance and reliability, such as pharmaceuticals and food and beverage production.

The system is also equipped for easy cleaning and maintenance, with tri-clover clamps allowing for quick disassembly. Customizable features like level probes, breather socks, and sampling ports offer additional flexibility to tailor the system to specific operational requirements, ensuring a perfect fit within diverse processing lines.

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DO2 Sensor optimized for bioprocesses

The Dissolved Oxygen sensor is a measuring device that informs about the dissolved oxygen in biotechnology processes, which is a basis for process optimization and control.

The AppliSens Low-Drift DO2 sensor from Getinge Applikon is specifically designed for long-term, stable, and accurate measurements in bioprocesses, such as fermentation and cell culture applications. Designed to withstand repeated sterilizations without failure.

The DO2 sensor has a titanium membrane module to minimize the measurement drift, and the available autoclave polarization module allows you to reduce start-up time for your cultures.

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Acidity sensor optimized for bioprocesses

The pH sensor from Getinge Applikon is constructed using FDA approved materials, like the non-toxic solid gel electrolyte. Furthermore this sensor has an internal pressure, which reduces cross contamination. The pH sensor is designed to withstand repeated sterilization cycles without failure.

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Optical Technology for Determining Oxygen Concentration Levels

Getinge Applikon’s Lumisens Sensors avoid these project delays because they use optical technology that is ready right away. This method takes accurate measurements even at low oxygen concentration levels, where polarographic sensors may be less accurate.

Lumisens optical sensors for the Getinge Applikon bioreactor range are suitable for 250mm to 3,000mm total volumes. Bespoke technology separates the glass sensor from the electronics, promoting long sensor life despite repeated sterilizations. Strong magnets accurately position the components together,

These optical sensors measure the phase shift between excitation and emission, which directly relates to partial oxygen pressure. This assures precision, reliability, low cross-sensitivity, and fast response to red light excitation.

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Measures Coffee Color for Quality Control

The Colorette 4 from PROBAT SE is a precision tool designed to elevate the quality control processes within coffee roasteries and production facilities. This state-of-the-art equipment employs reflection measurement with a white clock-pulsed LED to accurately determine the color of ground coffee, a critical factor in product consistency and quality. Tailored for use in various coffee applications such as espresso beans, instant coffee powders, and specialty blends, the Colorette 4 aids in making well-informed roasting and production decisions.

With user-friendly touch-screen operation, the device offers flexible scaling and calibration, providing readings not only in the standard Colorette scale but also in L*a*b and user-defined color spaces, enhancing its adaptability. The integration-ready design features Ethernet connectivity for seamless incorporation into existing control systems and USB ports for data storage, ensuring comprehensive data management.

Durably constructed for bench-top manual operations, the Colorette 4 consumes just 4 watts of power, emphasizing energy efficiency. It is an ideal solution for coffee roasteries, quality control laboratories, and R&D centers, providing reliable, precise color measurements crucial for maintaining high-quality end products.

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Monitors Real-Time Dissolution and Absorption

The MacroFLUX from Pion offers a unique solution for pharmaceutical and biopharmaceutical companies seeking efficient in-vitro dissolution-absorption testing. This system integrates seamlessly into your R&D and laboratory settings, utilizing a fiber-optic UV monitoring approach for real-time monitoring of dissolution and absorption concentrations in both donor and receiver compartments. With capabilities to handle various oral formulations like extended-release tablets and gel capsules, MacroFLUX supports formulation development and life-cycle management by ensuring batch-to-batch bioequivalence and product quality. The filter-supported artificial permeation membrane and Pion Acceptor Sink Buffer TM enable precise drug absorption studies. Easily customizable for different formulations, MacroFLUX assists in developing consistent and bioequivalent drug products, adhering to industry standards for analytical rigor.

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Inspects and Rejects Defective Products

The Quality Checker from Niverplast is a versatile camera system designed for comprehensive product inspection in the bakery, food production, and packaging sectors. It employs a multi-channel camera setup capable of evaluating multiple product types simultaneously, such as baguettes and bakery rolls, by assessing dimensions and surface characteristics. The system features an intuitive touchscreen interface for easy operation and can adapt to any production speed, ensuring seamless integration into your existing production line. With a compact design executed in stainless steel, the Quality Checker is both durable and easy to maintain. Equipped with servo-driven retract conveyors, it ensures precise rejection of non-compliant products, minimizing waste. Its capability to store and analyze inspection data helps in refining quality control processes over time. Customization options, such as the number of reject belts and SQL software tools, are available to fit specific production requirements.

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Controls and Monitors Bioreactor Cultivation Processes

The Livit Flex from Getinge is a configurable bioprocess controller designed for seamless integration into bioreactor systems. It simplifies the management of complex cell and microbial culture processes, supporting applications in pharmaceuticals and biotech. With capabilities for single or dual bioreactor control, it accommodates both single-use and multi-use setups, maximizing bench space efficiency. The incorporated intuitive Livit software platform allows for comprehensive data logging and process monitoring, enabling you to manage bioprocesses with precision. Supports a variety of operations including batch, fed-batch, perfusion, and continuous cultivation for end-products like monoclonal antibodies and vaccines. Its plug-and-play compatibility with a range of sensors and auxiliary devices enhances workflow efficiency, while ensuring adherence to GMP standards. The Livit Flex promises reliable performance, reduced operator error, and flexibility in meeting your unique R&D needs.

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Controls and Integrates Bioprocesses for Pilot and Production

The Pro-Control from Getinge is an adaptable bioprocess controller designed for pilot and production scale bioreactors. Featuring compatibility with DeltaV™, Siemens, and Allen Bradley PLCs, it ensures seamless integration within any facility. Ideal for producing monoclonal antibodies, CAR-T cell therapies, and lab-grown meat, it offers flexible configuration options tailored to specific process requirements. Capable of supporting single-use or sterilizable-in-place systems, Pro-Control manages operations from batch to continuous cultivation efficiently. It boasts a comprehensive set of sensors and actuators, ensuring precise measurement and control, while adhering to cGMP standards. The controller’s design optimizes both single-use and stainless-steel bioreactor applications, facilitating energy-efficient operations and streamlined cleaning.

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